Comparative analysis of chlorhexidine and listerine mouthwashes on buccal cell health: A clinical and cytological investigation

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Original Article

Author Details : Shraddha Shah, Jasuma Rai*, Monali Shah, Netra Shah

Volume : 10, Issue : 2, Year : 2024

Article Page : 95-100

https://doi.org/10.18231/j.ijohd.2024.020

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Abstract

Background: Mouthwashes are used routinely as adjunct to scaling and root planing. Chlorhexidine mouthwash is known as gold standard while Listerine is a widely used essential oil mouthwash. This study was done to evaluate and compare the genotoxic effect of Listerine with Chlorhexidine mouthwash on buccal cells.
Materials and Methods: It was a parallel design study with 20 participants in each group (Group 1: Chlorhexidine mouthwash and Group 2: Listerine mouthwash). Gingival index was recorded and buccal cells scraping were taken at baseline and 3 weeks after use of respective mouthwashes. The buccal cells were assessed for cytotoxicity using micronuclei test (under microscope at 100 x magnification) using Papanicolaou Stain.
Results: There was a statistically significant reduction seen in gingival index from baseline to 3 weeks in both the groups (p< 0> Conclusion: After a 3 weeks exposure, Listerine mouthwash showed less cytotoxicity on buccal cells as compared to Chlorhexidine mouthwash.
 

Keywords: Alcohol­based Mouthwash, Chlorhexidine, Cytotoxicity, Listerine, Mouthwash, Papanicolaou stains.

How to cite : Shah S, Rai J, Shah M, Shah N, Comparative analysis of chlorhexidine and listerine mouthwashes on buccal cell health: A clinical and cytological investigation. Int J Oral Health Dent 2024;10(2):95-100

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